In this sequel to the cult classic Zeiram the beautiful bounty hunter Iria once again finds her way to Earth. She has with her the supercomputer known as Bob, Along with a new combat android assistant. Unbeknownst to her the research team that built the combat android couldn't find a tactical program with enough cunning or fighting instinct to be useful. Therefore, they decided to cut corners and implant the androids brain with a vicious Zeiram alien! When the alien gains conscious control of the android, it begins using the machine's wide variety of weapon systems to terrorize Iria and her old human friends, Teppei and Kamiya. Now all three are trapped in a dimensional Zone by the monster and they will have to destroy it if they ever want to escape alive.